Nerve Growth Factor Alters the Sensitivity of Rat

نویسندگان

  • Xu-Dong Dong
  • Brian E. Cairns
چکیده

Hayes Wong 1 , Xu-Dong Dong 1,2 , Brian E. Cairns 1,3 5 6 1 Faculty of Pharmaceutical Sciences, The University of British Columbia, 7 2405 Wesbrook Mall, Vancouver, BC, Canada, V6T 1Z3 8 9 2 College of Stomatology, Tianjin Medical University, Tianjin 300070, 10 China 11 12 3 Center for Sensory Motor Interaction, Department of Health Science and 13 Technology , Faculty of Medicine, Aalborg University, Frederik Bajers Vej 14 7D3, 9220 Aalborg East, Denmark 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 Address for Correspondence: 30 31 Dr. Brian E. Cairns 32 Professor 33 Faculty of Pharmaceutical Sciences Building, 34 The University of British Columbia 35 2405 Wesbrook Mall Vancouver, BC, Canada, V6T 1Z3 36 Email: [email protected] 37 Phone: 604-822-7715 38 Articles in PresS. J Neurophysiol (August 13, 2014). doi:10.1152/jn.00327.2014

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Endurance Exercise Training on the Expression of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) Genes of the Cerebellum in Diabetic Rat

Objective: Few studies have been conducted on variations of the central nervous system of diabetic patients and much fewer investigations done on the cerebellum of diabetes patients. The current research aims to investigate the effect of endurance training on neurotrophic factors affecting the cerebellum in the diabetic rat. Materials and Methods: This study is experimental.Twenty Wistar rat w...

متن کامل

Effects of Different Psychotropic Agents on the Central Nerve Growth Factor Protein

Objective(s) Psychotropic medications produce their effects, in part, through increasing neurotrophin levels in the brain. Since studies concerning nerve growth factor (NGF) analysis have been limited in scope, in the current experiments we investigated the effects of diverse psychotropic agents on NGF protein levels in various brain regions of rat. Materials and Methods Male Wistar rats rec...

متن کامل

Effects of psychotropic drugs on nerve growth factor protein levels in the rat brain

Introduction: Psychotropic drugs exert their effects, in part, by increasing neurotrophin levels in the brain. Nerve growth factor (NGF) protein levels after treatment with only a limited number of psychotropics have been determined. The present study was designed in order to evaluate the effects of acute and chronic administration of different psychotropic drugs on NGF protein levels in fiv...

متن کامل

Ferulic acid, a phenolic compound with therapeutic effects in neuropsychiatric disorders, stimulates the production of nerve growth factor and endocannabinoids in rat brain

Introduction: Ferulic acid, a phenolic phytochemical with neuroprotective, anti-inflammatory, and antioxidant properties, has shown promising antidepressant-like effects in behavioral studies; however, its mechanism(s) of action have not been fully understood. Based on the contribution of nerve growth factor (NGF) and endocannabinoid signaling (eCBs) to the emotional or antidepressant activ...

متن کامل

Effect of Human Umbilical Cord Mesenchymal Stem Cells Transplantation on Nerve Fibers of A Rat Model of Endometriosis

Background Endometriosis is a common, benign, oestrogen-dependent, chronic gynaecological disorder associated with pelvic pain and infertility. Some researchers have identified nerve fibers in endometriotic lesions in women with endometriosis. Mesenchymal stem cells (MSCs) have attracted interest for their possible use for both cell and gene therapies because of their capacity for self-renewal ...

متن کامل

Effects of Nerve Growth Factor, Insulin- Like Growth Factor-I and Collagen Gel on Peripheral Nerve Channel: Sensory, Functional and Regeneration Through Piezoelectric Electrophysiologicalal Study

Purpose: The limited availability of donor sites for nerve grafts continues to stimulate research toward finding suitable alternatives. Material and Methods: In the following study, the effects of direct administration of Nerve Growth Factor (NGF), Insulin - Like Growth Factor - I (IGF-I) , or / and collagen gel into Polyvinylidene Fluride (PVDF) gap was tested in a rat sciatic nerve model. A ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014